ea0031p203 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013
Murambiwa Pretty
, Tufts Mark
, Mukaratirwa Samson
, Van Heerden Fanie R
, Murabayane Cephas T
Chloroquine (CHQ) the most frequently used drug for falciparum malaria in sub-Saharan Africa countries evokes adverse effects on glucose homeostasis and kidney function in African children. The complications can partly be ascribed to transiently high plasma CHQ concentrations following oral administration and/or malaria parasites. We have, however, reported that topical application of the pectin CHQ matrix patch releases CHQ into the bloodstream. Accordingly, the curr...